A rate of 100 Hz is comfortable at almost any size. The closest equivalent to a refresh rate on an LCD monitor is its frame rate, which is often locked at 60 fps.
Some models of monitors display a notice that the video signal uses an unsupported refresh rate.
Some LCDs support adapting their refresh rate to the current frame rate delivered by the graphics card.
CRT refresh rates have historically been an important factor in electronic game programming.
Traditionally, one of the principles of video/computer game programming is to avoid altering the computer's video buffer except during the vertical retrace.
On cathode ray tube (CRT) displays, increasing the refresh rate decreases flickering, thereby reducing eye strain.